Hereditary amyloidosis is a condition in which abnormal protein deposits (called amyloid) form in almost every tissue in the body, usually the heart, kidneys, and nervous system. These protein deposits damage the tissues and interfere with how organs work.
Amyloidosis - hereditary; Familial amyloidosis
Hereditary amyloidosis is passed down from parents to their children (inherited). For more information see: Primary amyloidosis.
Other types of amyloidosis are not inherited. They include:
Senile systemic, seen in patients older than 70
Spontaneous, which means it occurs without a known cause
Secondary, which means it results from diseases such as cancer of the blood cells (myeloma)
Chad Haldeman-Englert, MD, FACMG, Wake Forest School of Medicine, Department of Pediatrics, Section on Medical Genetics, Winston-Salem, NC. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.